Search Results | DrugBank Online (2024)

Luspatercept

Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.

Matched Mixtures name: … Oto End 10 ... Activir Duo 50 mg/g + 10 mg/g Creme …
Matched Products: … Cortizone 10 ... GENISONE 10 ... LIMICORT®-10 …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...

Matched Description: … In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. …
Matched Products: … มินาพีน 10 ... IMIPRAMINA 10 MG ... IMIPRAMIN-NEURAX 10 MG …

Potassium acetate

Matched Mixtures name: … AMINOPLASMAL® 10% E ... AMINOPLASMAL® 10% E ... AMINOPLASMAL-10% E INFUSION …

Fentanyl

Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone.Fentanyl's high potency has also...

Matched Products: … FENTANILO 500 MCG/10 ML ... ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... ABSTRAL 100MCG DILALTI TABLET, 10 TABLET …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...

Matched Products: … ไฮดรา 10 ... ไฮดรา 10 เอฟซี ... Hydralazine-10 Tab 10mg …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...

Matched Mixtures name: … Sentralopram AM-10 …
Matched Products: … Celexa 10 mg ... Citalopram-10 ... CITALOPRAM-NEURAX 10 MG …

Valerian

Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint...

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...

Matched Products: … .- 10 ... M BETA 10 ... MORPHINE HCL 10 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ (10 AMPUL) …

Methysergide

An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...

Matched Description: … It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.

Matched Products: … NALBUFINA CLORHIDRATO 10 MG/ML. ... Nubain 10 mg/ml Injektionslösung ... Nalbuphin Amomed 10 mg/ml Injektionslösung …

Mianserin

A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.

Matched Products: … เมลิน 10 ... เซอริน 10 มก ... MIANSERIN-NEURAX 10 MG …

Ambrosia artemisiifolia pollen

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]Acetylcysteine was granted FDA approval on 14 September 1963.

Matched Mixtures name: … Medi-10 ... AMINOVEN INFANT 10% ... AMINOPLASMAL-10% E INFUSION …
Matched Products: … ACT 300MG/3ML (%10) ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... FLUIMUCIL® 10 % ... XPECTO 300 MG SAŞE, 10 ADET …

Testolactone

An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...

Matched Iupac: … (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18 …
Matched Mixtures name: … OXYCODON COMP 1A 10/5MG ... OXYCODON COMP 1A 10/5MG ... OXYCODON COMP 1A 10/5MG …
Matched Products: … Supeudol 10 ... OXIDONA® 10 MG ... OxyNorm 10 mg Kapseln …

Miglustat

Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...

Matched Products: … OSEFLU 30 MG KAPSÜL, 10 ADET ... OSEFLU 45 MG KAPSÜL, 10 ADET ... OSEFLU 75 MG KAPSUL, 10 ADET …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...

Matched Mixtures name: … AMLONEB 10 MG/10 MG TABLET, 30 ADET ... AMLONEB 10 MG/10 MG TABLET, 90 ADET ... AMLONEB 10 MG/5 MG TABLET, 30 ADET …
Matched Products: … VASCURA 10 MG TABLET, 28 ADET ... VASOXEN 10 MG TABLET, 84 TABLET ... NEXIVOL 10 MG TABLET, 28 ADET …

Ciclopirox

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.

Matched Products: … NIBULEN 10 MG/G VAJİNAL KREM, 30 G ... NIBULEN 10 MG/ML DERMAL ÇÖZELTİ, 20 ML …

Anethole

Matched Categories: … Food Ingredients …

DL-alpha tocopheryl acetate

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...

Matched Products: … SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET ... SIMKELMA 10 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADET …

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...

Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide …

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...